Image credit: topag.mpg.deSept. 25, 2018 (MedicalXpress) -- The small SynuClean-D molecule interrupts the formation of the alpha-synuclein amyloid fibers responsible for the onset of Parkinson's disease, and reverts the neurodegeneration caused by the disease, researchers have found.
The study, headed by Universitat Autònoma de Barcelona researchers, was published in PNAS.
Parkinson's disease is the second most common incurable neurodegenerative disorder after Alzheimer's disease. It is characterized by the accumulation of protein deposits in dopaminergic neurons in the form of amyloid fibers.